Searchable abstracts of presentations at key conferences in endocrinology

ea0081p696 | Reproductive and Developmental Endocrinology | ECE2022

Comparison of three different AMH assays with AMH levels and follicle count in women with polycystic ovary syndrome

Moolhuijsen Loes , Louwers Yvonne , Laven Joop , Visser Jenny

Anti-Müllerian hormone (AMH) levels strongly correlate with the number of antral follicles in the ovary. In women with polycystic ovary syndrome (PCOS), this is reflected by significantly increased serum AMH levels. AMH levels are therefore suggested as a proxy for polycystic ovary morphology (PCOM) in PCOS diagnosis. Different assays are available to measure serum AMH levels. However, lack of a golden standard and the use of different antibodies to detect AMH, have led t...

ea0070oc9.3 | Reproductive and Developmental Endocrinology | ECE2020

Association between an AMH promoter polymorphism and serum AMH levels in PCOS patients

Moolhuijsen Loes , Louwers Yvonne V , Meun Cindy , Broer Linda , Uitterlinden Andre G , Sisk Ryan K , Dunaif Andrea , Laven Joop SE , Visser Jenny A

Introduction: Polycystic ovary syndrome (PCOS), the most common endocrine disorder in women of reproductive age, is diagnosed based on three criteria, including a polycystic ovarian morphology. Moreover, women with PCOS have elevated serum Anti-Müllerian Hormone (AMH) levels, a hormone known to correlate with follicle number. In addition, AMH production per follicle is suggested to be higher in PCOS. Little is known about AMH gene regulation. Hence, this study aims to inv...